Gut Microbiota – Host Interaction
Our lab is fascinated by the gut microbiota and their role in human physiology.
The mammalian gastrointestinal tract is the most populated organ of microbial symbionts and their associated bacteriophage. Recent studies have revealed the pivotal role of the gut microbiota in shaping the immune system, however, we still know little about the mechanistic molecular interactions among microbes and between microbes and the host. We are striving to elucidate the interactions between gut microbes, the mechanisms of their beneficial contributions to the host, and the role of bacteriophage in shaping the gut ecosystem. These studies may guide the design of productive microbial-derived molecules that will benefit the host during various health and disease states, as well as outline the design principles that govern the gut ecosystem.